I updated to WordPress 2.5 today. Looks to be working just fine, except for the tagging plugin that I use. I’ll have to wait until the plugin author releases a version that works well with 2.5 before being satisfied with updating.
Annoying things to me about the admin interface:
Can’t move boxes around in the write page anymore.
Still can’t extend the categories box to view all categories, but a “most used” makes it better.
Another plugins usage box is just thrown under all of it. I’d much rather have some of the stuff on the side.
Slow default tag autocomplete.
Horizontal Rules are still messed up.
More to come?